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1

EGFR Antagonists in Cancer Treatment

Ciardiello, Fortunato, Tortora, Giampaolo

Journal:

Boston Medical and Surgical Journal

Year:

2008

Language:

english

File:

PDF, 461 KB

english, 2008

2

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

Rittmeyer, Achim, Barlesi, Fabrice, Waterkamp, Daniel, Park, Keunchil, Ciardiello, Fortunato, von Pawel, Joachim, Gadgeel, Shirish M, Hida, Toyoaki, Kowalski, Dariusz M, Dols, Manuel Cobo, Cortinovis,

Journal:

Year:

2017

Language:

english

File:

PDF, 1.32 MB

english, 2017

3

Triple-Negative Breast Cancers: Systematic Review of the Literature on Molecular and Clinical Features with a Focus on Treatment with Innovative Drugs

Diana, Anna, Franzese, Elisena, Centonze, Sara, Carlino, Francesca, Corte, Carminia Maria Della, Ventriglia, Jole, Petrillo, Angelica, De Vita, Ferdinando, Alfano, Roberto, Ciardiello, Fortunato, Ordi

Journal:

Current Oncology Reports

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

4

Kisspeptin and Cancer: Molecular Interaction, Biological Functions, and Future Perspectives

Ciaramella, Vincenza, Della Corte, Carminia Maria, Ciardiello, Fortunato, Morgillo, Floriana

Journal:

Frontiers in Endocrinology

Year:

2018

Language:

english

File:

PDF, 512 KB

english, 2018

5

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer

Kopetz, Scott, Grothey, Axel, Yaeger, Rona, Van Cutsem, Eric, Desai, Jayesh, Yoshino, Takayuki, Wasan, Harpreet, Ciardiello, Fortunato, Loupakis, Fotios, Hong, Yong Sang, Steeghs, Neeltje, Guren, Torm

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 309 KB

english, 2019

6

Epidermal growth factor-related peptides and their receptors in human malignancies

David S. Salomon, Ralf Brandt, Fortunato Ciardiello, Nicola Normanno

Journal:

Critical Reviews in Oncology/Hematology

Year:

1995

Language:

english

File:

PDF, 6.64 MB

english, 1995

7

Rational bases for the development of EGFR inhibitors for cancer treatment

Roberto Bianco, Teresa Gelardi, Vincenzo Damiano, Fortunato Ciardiello, Giampaolo Tortora

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2007

Language:

english

File:

PDF, 583 KB

english, 2007

8

Key cancer cell signal transduction pathways as therapeutic targets

Roberto Bianco, Davide Melisi, Fortunato Ciardiello, Giampaolo Tortora

Journal:

European Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 115 KB

english, 2006

9

ALK inhibitors in the treatment of advanced NSCLC

Gridelli, Cesare, Peters, Solange, Sgambato, Assunta, Casaluce, Francesca, Adjei, Alex A., Ciardiello, Fortunato

Journal:

Cancer Treatment Reviews

Year:

2014

Language:

english

File:

PDF, 316 KB

english, 2014

10

Novel investigational drugs for gastric cancer

Vecchione, Loredana, Orditura, Michele, Ciardiello, Fortunato, De Vita, Ferdinando

Journal:

Expert Opinion on Investigational Drugs

Year:

2009

Language:

english

File:

PDF, 445 KB

english, 2009

11

The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer

Van Cutsem, Eric, Mayer, Robert J., Laurent, Stéphanie, Winkler, Robert, Grávalos, Cristina, Benavides, Manuel, Longo-Munoz, Federico, Portales, Fabienne, Ciardiello, Fortunato, Siena, Salvatore, Yama

Journal:

European Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 463 KB

english, 2018

12

Efficacy of Sym004 in Patients With Metastatic Colorectal Cancer With Acquired Resistance to Anti-EGFR Therapy and Molecularly Selected by Circulating Tumor DNA Analyses

Montagut, Clara, Argilés, Guillem, Ciardiello, Fortunato, Poulsen, Thomas T., Dienstmann, Rodrigo, Kragh, Michael, Kopetz, Scott, Lindsted, Trine, Ding, Cliff, Vidal, Joana, Clausell-Tormos, Jenifer,

Journal:

Year:

2018

Language:

english

File:

PDF, 466 KB

english, 2018

13

Carcinogenesis as a Result of Multiple Inflammatory and Oxidative Hits: a Comprehensive Review from Tumor Microenvironment to Gut Microbiota

Morgillo, Floriana, Dallio, Marcello, Della Corte, Carminia Maria, Gravina, Antonietta Gerarda, Viscardi, Giuseppe, Loguercio, Carmelina, Ciardiello, Fortunato, Federico, Alessandro

Journal:

Year:

2018

Language:

english

File:

PDF, 808 KB

english, 2018

14

What’s New in Gastric Cancer: The Therapeutic Implications of Molecular Classifications and Future Perspectives

Tirino, Giuseppe, Pompella, Luca, Petrillo, Angelica, Laterza, Maria, Pappalardo, Annalisa, Caterino, Marianna, Orditura, Michele, Ciardiello, Fortunato, Galizia, Gennaro, De Vita, Ferdinando

Journal:

International Journal of Molecular Sciences

Year:

2018

Language:

english

File:

PDF, 287 KB

english, 2018

15

PARP inhibitors in ovarian cancer

Franzese, Elisena, Centonze, Sara, Diana, Anna, Carlino, Francesca, Guerrera, Luigi Pio, Di Napoli, Marilena, De Vita, Ferdinando, Pignata, Sandro, Ciardiello, Fortunato, Orditura, Michele

Journal:

Cancer Treatment Reviews

Year:

2019

Language:

english

File:

PDF, 1.05 MB

english, 2019

16

Transfection with a CRIPTO anti-sense plasmid suppresses endogenous CRIPTO expression and inhibits transformation in a human embryonal carcinoma cell line

Gustavo Baldassarre, Caterina Bianco, Giampaolo Tortora, Angela Ruggiero, Mark Moasser, Ethan Dmitrovsky, A. Raffaele Bianco, Fortunato Ciardiello

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 755 KB

english, 1996

17

Anti-sense oligonucleotides directed against EGF-related growth factors enhance anti-proliferative effect of conventional anti-tumor drugs in human colon-cancer cells

Antonella De Luca, Mouna P. Selvam, Claudia Sandomenico, Stefano Pepe, A. Raffaele Bianco, Fortunato Ciardiello, David S. Salomon, Nicola Normanno

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 185 KB

english, 1997

18

EGF-related peptides are involved in the proliferation and survival of MDA-MB-468 human breast carcinoma cells

Antonella De Luca, Amelia Casamassimi, Mouna P. Selvam, Simona Losito, Fortunato Ciardiello, Sudhir Agrawal, David S. Salomon, Nicola Normanno

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 194 KB

english, 1999

19

Resistance to taxanes is induced by c-erbB-2 overexpression in human MCF-10A mammary epithelial cells and is blocked by combined treatment with an antisense oligonucleotide targeting type I protein kinase A

Fortunato Ciardiello, Rosa Caputo, Grazia Pomatico, Michelino De Laurentiis, Sabino De Placido, A. Raffaele Bianco, Giampaolo Tortora

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 122 KB

english, 2000

20

A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer

Giampaolo Tortora, Rosa Caputo, Vincenzo Damiano, Roberto Bianco, Jiangdong Chen, Sudhir Agrawal, A. Raffaele Bianco, Fortunato Ciardiello

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 150 KB

english, 2000

21

Elevated perioperative serum vascular endothelial growth factor levels in patients with colon carcinoma

Ferdinando De Vita, Michele Orditura, Eva Lieto, Stefania Infusino, Floriana Morgillo, Erika Martinelli, Paolo Castellano, Ciro Romano, Fortunato Ciardiello, Giuseppe Catalano, Carlo Pignatelli, Genna

Journal:

Year:

2004

Language:

english

File:

PDF, 123 KB

english, 2004

22

Author Reply

Ferdinando De Vita, Michele Orditura, Gennaro Galizia, Fortunato Ciardiello, Giuseppe Catalano

Journal:

Year:

2004

Language:

english

File:

PDF, 59 KB

english, 2004

23

Potential role of molecularly targeted therapy in the management of advanced nonsmall cell lung carcinoma in the elderly

Cesare Gridelli, Erminia Massarelli, Paolo Maione, Antonio Rossi, Roy S. Herbst, Amir Onn, Fortunato Ciardiello

Journal:

Year:

2004

Language:

english

File:

PDF, 151 KB

english, 2004

24

Flow-cytometric detection of the RIα subunit of type I cAMP-dependent protein kinase in human cells

Dr. Stefano Pepe, Angela Ruggiero, Giampaolo Tortora, Fortunato Ciardiello, Corrado Garbi, Hiroshi Yokozaki, Yoon S. Cho-Chung, Timothy Clair, Bjorn S. Skalhegg, Angelo R. Bianco

Journal:

Cytometry Part A

Year:

1994

Language:

english

File:

PDF, 680 KB

english, 1994

25

ZD1839 (IRESSA), an EGFR-selective tyrosine kinase inhibitor, enhances taxane activity in bcl-2 overexpressing, multidrug-resistant MCF-7 ADR human breast cancer cells

Fortunato Ciardiello, Rosa Caputo, Gaetano Borriello, Donatella Del Bufalo, Annamaria Biroccio, Gabriella Zupi, A. Raffaele Bianco, Giampaolo Tortora

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 339 KB

english, 2002

26

Antisense oligonucleotides targeting the epidermal growth factor receptor inhibit proliferation, induce apoptosis, and cooperate with cytotoxic drugs in human cancer cell lines

Fortunato Ciardiello, Rosa Caputo, Teresa Troiani, Gaetano Borriello, Ekambar R. Kandimalla, Sudhir Agrawal, John Mendelsohn, A. Raffaele Bianco, Giampaolo Tortora

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 210 KB

english, 2001

27

Chronic inflammation and oxidative stress in human carcinogenesis

Alessandro Federico, Floriana Morgillo, Concetta Tuccillo, Fortunato Ciardiello, Carmela Loguercio

Journal:

International Journal of Cancer

Year:

2007

Language:

english

File:

PDF, 180 KB

english, 2007

28

Over-expression of the epidermal growth factor receptor in human breast cancer cells fails to induce an Estrogen-independent phenotype

Eva M. Valverius, Thierry Velu, Vidya Shankar, Fortunato Ciardiello, Nancy Kim, David S. Salomon

Journal:

International Journal of Cancer

Year:

1990

Language:

english

File:

PDF, 993 KB

english, 1990

29

Down-regulation of riα subunit of camp-dependent protein kinase induces growth inhibition of human mammary epithelial cells transformed by c-ha-ras and c-erbb-2 proto-oncogenes

Fortunato Ciardiello, Stefano Pepe, Caterina Bianco, Gustavo Baldassarre, Angela Ruggiero, Cataldo Bianco, Mouna P. Selvam, A. Raffaele Bianco, Giampaolo Tortora

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 716 KB

english, 1993

30

Infection with a transforming growth factor α anti-sense retroviral expression vector reduces the in vitro growth and transformation of a human colon cancer cell line

Fortunato Ciardiello, Catcrina Bianco, Nicola Normanno, Gustavo Baldassarre, Stefano Pepe, Giampaolo Tortora, A. Raffaele Bianco, David S. Salomon

Journal:

International Journal of Cancer

Year:

1993

Language:

english

File:

PDF, 819 KB

english, 1993

31

Response of normal and oncogene-transformed human mammary epithelial cells to transforming growth factor β1 (TGF-β1): Lack of growth-inhibitory effect on cells expressing the simian virus 40 large-t antigen

Fulvio Basolo, Lisa Fiore, Fortunato Ciardiello, Simonetta Calvo, Gabriella Fontanini, Pier Giulio Conaldi, Antonio Toniolo

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 825 KB

english, 1994

32

Induction of multidrug resistance (MDR) by transfection of MCF-10A cell line with c-Ha-ras and c-erbB-2 oncogenes

Antonietta R. M. Sabbatini, Fulvio Basolo, Paola Valentini, Letizia Mattii, Simonetta Calvo, Lisa Fiore, Fortunato Ciardiello, Mario Petrini

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 595 KB

english, 1994

33

Differential effects of protein kinase a sub-units on chinese-hamster-ovary cell cycle and proliferation

Giampaolo Tortora, Stefano Pepe, Caterina Bianco, Vincenzo Damiano, Angela Ruggiero, Gustavo Baldassarre, Claudia Corbo, Yoon Sang Cho-Chung, A. Raffaele Bianco, Fortunato Ciardiello

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 601 KB

english, 1994

34

NM23 gene expression correlates with cell growth rate and S-phase

Maria A. Caligo, Giovanna Cipollini, Lisa Fiore, Simonetta Calvo, Fulvio Basolo, Paola Collecchi, Fortunato Ciardiello, Stefano Pepe, Mario Petrini, Generoso Bevilacqua

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 1.04 MB

english, 1995

35

α-interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells

Michele Caraglia, Annalisa Leardi, Stefania Corradino, Fortunato Ciardiello, Alfredo Budillon, Rosario Guarrasi, Angelo R. Bianco, Pierosandro Tagliaferri

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 839 KB

english, 1995

36

Amphiregulin anti-sense oligodeoxynucleotides inhibit growth and transformation of a human colon carcinoma cell line

Nicola Normanno, Mouna P. Selvam, Caterina Bianco, Vincenzo Damiano, Ernesto de Angelis, Michele Grassi, Gabriella Magliulo, Giampaolo Tortora, David S. Salomon, Fortunato Ciardiello

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 604 KB

english, 1995

37

Invasive phenotype of MCF10A cells overexpressing c-Ha-ras and c-erbB-2 oncogenes

Daniela Giunciuglio, Martine Culty, Gianfranco Fassina, Luciana Masiello, Antonella Melchiori, Giuseppina Paglialunga, Gloria Arand, Fortunato Ciardiello, Fulvio Basolo, Erik W. Thompson, Adriana Albi

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 2.20 MB

english, 1995

38

Differential growth factor expression in transformed mouse NIH-3T3 cells

Fortunato Ciardiello, Eva M. Valverius, G. Luca Colucci-D'Amato, Nancy Kim, Robert H. Bassin, David S.Salomon

Journal:

Journal of Cellular Biochemistry

Year:

1990

Language:

english

File:

PDF, 954 KB

english, 1990

39

Stromal influences on transformation of human mammary epithelial cells overexpressing c-myc and SV40T

Eva M. Valverius, Fortunato Ciardiello, Nils-Erik Heldin, Bruno Blondel, Giorgio Merlo, Gilbert Smith, Martha R. Stampfer, Marc E. Lippman, Robert B. Dickson, David S. Salomon

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 1.37 MB

english, 1990

40

Trying to compose the puzzle with all the pieces: Epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

Massimo Di Maio, Cesare Gridelli, Nicola Normanno, Francesco Perrone, Fortunato Ciardiello

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

41

Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells

Tina Cascone, Maria Pia Morelli, Floriana Morgillo, Woo-Young Kim, Gabriella Rodolico, Stefano Pepe, Liberato Berrino, Ho-Young Lee, John V. Heymach, Fortunato Ciardiello

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 356 KB

english, 2008

42

Synergistic anti-proliferative and pro-apoptotic activity of combined therapy with bortezomib, a proteasome inhibitor, with anti-epidermal growth factor receptor (EGFR) drugs in human cancer cells

Tina Cascone, Maria Pia Morelli, Floriana Morgillo, Woo-Young Kim, Gabriella Rodolico, Stefano Pepe, Giampaolo Tortora, Liberato Berrino, Ho-Young Lee, John V. Heymach, Fortunato Ciardiello

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 29 KB

english, 2008

43

p27 downregulation and metallothionein overexpression in gastric cancer patients are associated with a poor survival rate

Gennaro Galizia, Francesca Ferraraccio, Eva Lieto, Michele Orditura, Paolo Castellano, Vincenzo Imperatore, Giovanni La Manna, Margherita Pinto, Fortunato Ciardiello, Anna La Mura, Ferdinando De Vita

Journal:

Journal of Surgical Oncology

Year:

2006

Language:

english

File:

PDF, 173 KB

english, 2006

44

Transformation of an established mouse mammary epithelial cell line following transfection with a human transforming growth factor alpha cDNA

Vidya Shankar, Fortunato Ciardiello, Nancy Kim, Rik Derynck, Daniel S. Liscia, Giorgio Merlo, Beatrice C. Langton, Donald Sheer, Robert Callahan, Robert H. Bassin, Marc E. Lippman, Nancy Hynes, David

Journal:

Molecular Carcinogenesis

Year:

1989

Language:

english

File:

PDF, 1.15 MB

english, 1989

45

Additive effects of c-erbB-2, c-Ha-ras, and transforming growth factor-α genes on in vitro transformation of human mammary epithelial cells

Fortunato Ciardiello, Marco Gottardis, Fulvio Basolo, Stefano Pepe, Nicola Normanno, Robert B. Dickson, A. Raffaele Bianco, David S. Salomon

Journal:

Molecular Carcinogenesis

Year:

1992

Language:

english

File:

PDF, 1.01 MB

english, 1992

46

ZD6474, an inhibitor of VEGFR and EGFR tyrosine kinase activity in combination with radiotherapy

Barbara Frederick, Dan Gustafson, Cataldo Bianco, Fortunato Ciardiello, Isaiah Dimery, David Raben

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

47

The use of xenograft models for the selection of cancer treatments with the EGFR as an example

Teresa Troiani, Clorinda Schettino, Erika Martinelli, Floriana Morgillo, Giampaolo Tortora, Fortunato Ciardiello

Journal:

Critical Reviews in Oncology/Hematology

Year:

2008

Language:

english

File:

PDF, 187 KB

english, 2008

48

Vascular endothelial growth factor and neo-angiogenesis in H. pylori gastritis in humans

Concetta Tuccillo, Antonio Cuomo, Alba Rocco, Erika Martinelli, Stefania Staibano, Massimo Mascolo, Antonietta G Gravina, Gerardo Nardone, Vittorio Ricci, Fortunato Ciardiello, Camillo Del Vecchio Bla

Journal:

The Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 352 KB

english, 2005

49

The role of amphiregulin in breast cancer

David S. Salomon, Nicola Normanno, Fortunato Ciardiello, Ralf Brandt, Mohammed Shoyab, George J. Todaro

Journal:

Breast Cancer Research and Treatment

Year:

1995

Language:

english

File:

PDF, 1021 KB

english, 1995

50

Mechanisms of resistance to EGFR inhibitors

Roberto Bianco, Teresa Gelardi, Vincenzo Damiano, Fortunato Ciardiello, Giampaolo Tortora

Journal:

Targeted Oncology

Year:

2007

Language:

english

File:

PDF, 142 KB

english, 2007